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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Tri(amino-PEG5-amide)-amine is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to selectively degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
For research use only
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Tolterodine tartrate is an mAChR inhibitor and substrate for cytochrome P450 enzymes, used in research for urinary tract infections and overactive bladder. It competitively binds acetylcholine, reducing sympathetic excitation and inhibiting involuntary bladder muscle contraction.
Inhibits muscarinic acetylcholine receptors
Substrate for cytochrome P450 enzymes
Reduces sympathetic excitation
Inhibits involuntary bladder muscle contraction
Restores Nrf2/NF-κB signaling pathway
Protects against inflammatory response and ferroptosis
Ameliorates LPS-induced oxidative stress
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Azido-PEG5-alcohol is a polyethylene glycol (PEG) linker with a terminal azide and a terminal alcohol, used for bioconjugation and linker installation. The azide group enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions, while the PEG5 spacer improves solubility and flexibility for conjugation workflows.
Terminal azide enables CuAAC and SPAAC click reactions.
PEG5 spacer increases solubility and reduces steric hindrance.
Suitable for use as a non-cleavable linker in conjugation chemistry.
Colorless to light yellow liquid with high purity.
Stable under recommended storage conditions for long-term use.
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Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and a 3-unit PEG linker, commonly used in PROTAC technology. This product is intended for research use only and has not been fully validated for medical applications.
E3 ligase ligand-linker conjugate
Incorporates Pomalidomide based cereblon ligand
Utilizes a 3-unit PEG linker
Used in PROTAC technology
Targets Cereblon
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